Support your nightly relaxation.
The Sereniser was developed in collaboration with longevity researchers from Switzerland. It follows a multidimensional approach based on findings from neuroscience and chronobiology.
Sereniser | Rest deeper, rise stronger | AVEA life
4.8/5
Sereniser
Sereniser is your non-hormonal solution that supports nightly relaxation.* The Sereniser consists of a groundbreaking blend of synergistic ingredients, including Safr'Inside™ (saffron extract), Holixer™ (basil extract), Serezin™ (ginger and frankincense extract), L-theanine, magnesium bisglycinate, and vitamin B6 ensuring that you wake up full of energy every morning.**
* Magnesium contributes to normal muscle function. Magnesium and vitamin B6 contribute to normal nervous system and psychological function.
** Magnesium and vitamin B6 contribute to normal energy metabolism and the reduction of fatigue.
Supports relaxation
Promotes recovery
Magnesium contributes to normal muscle function and vitamin B6 contributes to normal nervous system and psychological function, supporting relaxation. The combination of valuable plant extracts of saffron and holy basil is based on findings from traditional practice and modern science.
Magnesium contributes to normal muscle function and vitamin B6 contributes to normal nervous system and psychological function, supporting relaxation. The combination of valuable plant extracts of saffron and holy basil is based on findings from traditional practice and modern science.
Vitamin B6 and magnesium help the body recover and reduce tiredness and fatigue.
Non-habit forming
Best quality and purity
In contrast to melatonin, the active ingredients in the Sereniser do not produce a habituation effect and sustainably support relaxation.
In contrast to melatonin, the active ingredients in the Sereniser do not produce a habituation effect and sustainably support relaxation.
We only use ingredients from leading raw material producers with the highest bioavailability. All products are tested for purity in an independent laboratory in Switzerland.
Supports relaxation
Magnesium contributes to normal muscle function and vitamin B6 contributes to normal nervous system and psychological function, supporting relaxation. The combination of valuable plant extracts of saffron and holy basil is based on findings from traditional practice and modern science.
Promotes recovery
Vitamin B6 and magnesium help the body recover and reduce tiredness and fatigue.
Non-habit forming
In contrast to melatonin, the active ingredients in the Sereniser do not produce a habituation effect and sustainably support relaxation.
Best quality and purity
We only use ingredients from leading raw material producers with the highest bioavailability. All products are tested for purity in an independent laboratory in Switzerland.
Sleep science 101
The science behind deep, restorative sleepSleep is not just about duration – it’s about depth, cycles, and consistency.
Most of us know we need 7–9 hours of sleep, but not all sleep is created equal.
Throughout the night, your brain moves through a series of stages—light sleep, deep sleep (also known as slow-wave sleep), and REM sleep (when most dreaming occurs). These stages cycle roughly every 90 minutes and each plays a distinct role in how your body and mind recover.
- Light sleep helps the body relax and stabilise, preparing for deeper, restorative sleep stages.
- Deep sleep is when the body repairs muscle, restores energy, and strengthens the immune system.
- REM sleep supports memory consolidation, emotional processing, and cognitive performance.
But as we age, our sleep architecture begins to shift.
Older adults tend to spend more time in lighter stages and less in slow-wave and REM sleep. The amount of deep sleep for mature adults declines steadily – making sleep more fragmented and less restorative, even if you’re getting enough hours.
At the same time, the circadian rhythm, your body’s internal clock, becomes less stable. Many people experience a shift known as phase advance, feeling sleepy earlier in the evening and waking earlier in the morning, often before they’ve had adequate rest. Hormonal shifts, especially for women during perimenopause and menopause, also contribute to this disruption.
These changes don’t just impact how rested you feel – they affect your long-term health.
Deep, uninterrupted sleep is strongly linked to healthy ageing and longevity. It influences immune resilience, hormone balance, metabolic function, and even how efficiently the brain clears out waste through the glymphatic system.
When sleep becomes shallow or inconsistent, the body’s ability to repair, regulate, and renew itself also begins to decline.
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To counter these changes, many people turn to over-the-counter melatonin or prescription sedatives (often referred to as sleeping pills) or antihistamines.
But most of these solutions work by artificially sedating the brain, and may cause more harm than good – particularly as we age.
Melatonin is a hormone your brain produces in response to darkness. It signals that it’s time to wind down – but it doesn’t control how long you sleep or how deeply you rest. When taken in high doses, at the wrong time, or for extended periods, melatonin can:
- Disrupt your body’s natural melatonin production
- Disrupt your internal sleep-wake rhythm even further
- Cause residual drowsiness, vivid dreams, or headaches over time
Sedatives go a step further by suppressing brain activity altogether – inducing unconsciousness, but not true sleep. These drugs can interrupt your brain’s natural sleep architecture, preventing you from reaching slow-wave and REM sleep – the very stages responsible for memory consolidation, emotional regulation, and immune function.
Over time, the use of sedatives has also been linked to increased risk of cognitive decline, particularly in older adults.
Instead of forcing sleep, the goal should be to support the systems that naturally regulate it – including your circadian rhythm, nervous system, cortisol cycles, and neurotransmitters like GABA and serotonin.
This is what allows the body to access real, uninterrupted sleep and with it, the recovery, clarity, and long-term resilience it was designed for.
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Women experience sleep differently – and this becomes especially noticeable during perimenopause and menopause. Despite maintaining consistent routines, many begin to experience new or worsening sleep disruptions: difficulty staying asleep, early morning awakenings, or waking feeling less restored than before.
These changes are not imagined – they’re physiological.
As estrogen and progesterone begin to decline, they also influence the release and amount of other hormones and neurotransmitters that regulate sleep:
- Melatonin, which governs circadian rhythm
- Cortisol, which impacts stress and sleep fragmentation
- Serotonin, which helps calm the nervous system and initiate deep rest
When these hormones and neurotransmitters are thrown out of balance, sleep becomes lighter, more fragmented, and more easily disrupted. Hot flashes, increased nighttime cortisol, and changes in thermoregulation all add to the challenge – even for women who’ve never struggled with sleep before.
Sleep during menopause is also more sensitive to stress, screen exposure, diet, and even small environmental changes. The nervous system becomes more reactive, and the body may cycle in and out of sleep stages more frequently.
But these shifts go beyond night-time rest.
Because deep sleep plays a key role in hormone regulation, immune resilience, and cognitive repair, a decline in sleep quality during menopause can also impact long-term energy, clarity, and healthy ageing.
And yet, most sleep solutions aren’t designed with women in mind — let alone with the complexity of hormonal transitions.
Understanding the root causes of disrupted sleep in midlife is essential to supporting better rest – and better health – for decades to come.
Feel the dıfference
Many users describe feeling more balanced and at ease with Sereniser.*
93%
report an increase in general well-being*2×
wake up more refreshed in the morning*37%
experienced more serenity after 8 weeks**4 weeks
After just 4 weeks, many felt noticeably less exhausted***Magnesium contributes to normal muscle function. Magnesium and vitamin B6 contribute to normal nervous system and psychological function. Magnesium and vitamin B6 contribute to normal energy metabolism and the reduction of fatigue.
Sereniser
60 capsules per bottle
Sereniser
60 capsules per bottle- A blend of synergistic ingredients, including Safr'Inside™ (saffron extract), Holixer™ (basil extract), Serezin™ (ginger and frankincense extract), L-theanine, magnesium bisglycinate, and vitamin B6, to support relaxation and nightly rest.*
- 90-day money-back guarantee
*Magnesium contributes to normal muscle function. Magnesium and vitamin B6 contribute to normal nervous system and psychological function.
90 days money-back guarantee
Take 2 capsules with water around 1-2 hours before bedtime. If you’re sensitive to supplements, you can start with 1 capsule for a few nights and adjust as needed.
Developed in Switzerland
Formulated by Experts
Sustainable Packaging
Clinically Tested Ingredients
Vegan
Halal
Active ingredients:
Blend of Frankincense and Ginger Extract (Serezin™) 300mg, Holy Basil Extract (Holixer™) 250mg, Green Tea Extract 175mg of which L-Theanine 100mg, Magnesium (from Magnesium Bisglycinate) 56.25mg, Saffron Extract (Safr’Inside™) 30mg, Vitamin B6 (Pyridoxal 5-Phosphate) 1.4mg
Other ingredients:
- Microcrystalline cellulose as bulking agent to ensure the capsule is completely full (active ingredients may not take up enough space), aiding in consistent manufacturing and dosing
- Magnesium salts of fatty acids as anti-caking agent to ensure that powdered contents remain free-flowing (important for manufacturing) and to help achieve a consistent mixture of ingredients within the capsule (ensuring proper dosage)
- Hydroxypropyl methyl cellulose (HPMC) as glazing agent in form of a vegetable capsule shell
Food Supplement with Botanicals, Magnesium and Vitamin B6
Ingredients: Blend of Frankincense and Ginger Extract (Serezin™), Magnesium Bisglycinate, Holy Basil Extract (Holixer™), Glazing Agent (Hydroxypropyl Methyl Cellulose), Green Tea Extract with L-Theanine, Bulking Agent (Microcrystalline Cellulose), Saffron Extract (Safr’Inside™), Anti-Caking Agent (Magnesium Salts of Fatty Acids), Pyridoxal 5'-Phosphate.
Do not exceed recommended daily intake. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Not suitable for pregnant or breastfeeding women, children or adolescents. If you have a medical condition or are taking medication, please consult a doctor before use.
Store in a cool, dry place. Keep out of reach of young children.
Distributer: AV Longevity Distribution (Schweiz) GmbH, Schöntal 634, 9308 Lömmenschwil, CH.
Quantity: 43 g (60 x 0.72 g)
At AVEA, we prioritise transparency and quality. We develop and manufacture the finished products with globally sourced raw materials in state-of-the-art, GMP-certified facilities in Switzerland that are regularly audited by authorities. Every batch is rigorously double-tested for purity by an independent Swiss lab. We go beyond standard labelling to provide detailed information, and our customer service team is available for any questions or test result requests.
| Active ingredients | Supplier | Production method |
|---|---|---|
| Green Tea Extract with L-Theanine | JiangXi Nanyu Biotechnology Co., Ltd. | Camellia sinensis leaf extraction |
| Blend of Frankincense and Ginger Extract (Serezin™) | Laila Nutraceuticals Ltd. | Boswellia serrata gum-resin and Zingiber officinale rhizome extraction |
| Holy Basil Extract (Holixer™) | Vivatis Pharma GmbH | Ocimum tenuiflorum leaf extraction |
| Magnesium Bisglycinate (Magnesium) | Nutraceuticals Group Europe Ltd. | Chemical synthesis |
| Saffron Extract (Safr’Inside™) | ACTIV'INSIDE | Crocus sativus stigma extraction |
| Pyridoxal 5-Phosphate (Vitamin B6) | ECSA Chemicals AG | Chemical synthesis |
We ship worldwide, free delivery above 50£/€/CHF, 5-10 days from dispatch depending on your region.
Sereniser
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Discover the science behind the Sereniser
Developed by leading scientists in Switzerland, the Sereniser combines valuable plant extracts such as Safr’Inside™, Holixer™ and Serezin™ with L-theanine, magnesium bisglycinate and vitamin B6.
See full supplement facts
Safr’Inside™
30 mgA patented, standardized, and highly bioavailable saffron extract. Saffron has been used for centuries in Chinese, Indian, and European medicine.
Holixer™
250 mgA clinically tested extract from holy basil (also known as Indian basil). Holy basil is widely used in traditional Ayurvedic medicine.
Serezin™
300 mgAn innovative combination of natural Ginger and frankincense extracts. Frankincense contains various essential oils, polysaccharides and terpenes which are said to have positive effects in traditional medicine.
L-Theanine
100 mgA naturally occurring amino acid from green tea that is responsible for the calm, focused state experienced after drinking green tea.
Magnesium Bisglycinate
56.25 mgMagnesium also occurs naturally in foods like sunflower seeds. We use a particularly bioavailable form: magnesium bisglycinate. Because it's bound to glycine, an amino acid, it's especially gentle on the stomach and readily absorbed by the body. Magnesium contributes to normal muscle function, the normal function of the nervous system, and normal psychological function. It also plays a role in energy metabolism and helps reduce tiredness and fatigue.
Vitamin B6
1.4 mgAn essential cofactor in the formation of GABA and serotonin – two key neurotransmitters that regulate mood and sleep. Naturally found in kernels and nuts, vitamin B6 supports the normal function of the nervous system and psychological function. Vitamin B6 also plays a role in energy metabolism and contributes to the reduction of tiredness and fatigue.
See full supplement facts
See full supplement facts
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Take 2 capsules with water approximately 1–2 hours before bedtime. If you are sensitive to supplements, you can start with 1 capsule for a few nights and adjust the dosage as needed.
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No – the Sereniser does not contain melatonin and is non-sedating. It does not disturb your natural sleep. Most users wake up clear-headed, refreshed, and rested.
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The Sereniser is made with clinically studied plant extracts. It contains no sedatives or hormones, and there's no risk of rebound effects if you stop taking it.
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Yes, the Sereniser is a vegan supplement and does not contain any ingredients of animal origin.
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Authorities in different countries have strict regulations on health-related claims about supplement ingredients. Often, only claims from a list approved by the authorities may be made.
If one of our products lists only a few or no indications of potential benefits, this is because there are currently no authority-approved claims for the ingredients.However, you are free to do your own research in reliable sources and form your own opinion about the ingredients.
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The Sereniser is generally well tolerated and can be taken together with other supplements. If you are currently taking sleep medication or have a diagnosed sleep disorder, we strongly recommend that you speak to your doctor, healthcare provider, or other healthcare professional before taking Sereniser. They can assess possible interactions and ensure that the combination is suitable and safe for you.
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Your product will be dispatched from our UK warehouse within 24 hours.
We ship internationally and offer multiple shipping options:
We offer FREE shipping from an order value of £50 through postal route as well as faster shipping options through commercial routes, depending on the destination country. Shipping options with estimated delivery time and final cost are calculated and shown during checkout.
If your country is not part of our shipping destinations, contact our customer service (support@avea-life.com) and we will look into our options. -
We recommend taking the food supplement regularly for at least three months to get the most out of the ingredients.
If you're not satisfied after that, you can take advantage of our 90-day money-back guarantee.
