As we age, the natural renewal process slows down. The protective barrier loses strength, moisture is lost more easily, and external influences such as oxidative stress have a greater effect - often long before visible changes appear.
SkinSpan™ was developed to go beyond pure moisturizing or plumping through external skin care: it combines state-of-the-art plant substances with effective micronutrients for the skin - for a well-cared-for, vital appearance.

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SkinSpan™
SkinSpan™ combines clinically tested ingredients that combine cutting-edge research with beauty innovation. The formula was developed to support beauty from within - with an approach that goes beyond simply replacing collagen.
SkinSpan™ provides Ceramosides™, a patented plant-based ceramide complex derived from wheat seeds. Ceramides are natural components of the skin's lipid barrier. SkinSpan™ also contains 200 mg of hyaluronic acid, which can bind large amounts of water and is also a component of the skin.
SkinSpan™ provides Ceramosides™, a patented plant-based ceramide complex derived from wheat seeds. Ceramides are natural components of the skin's lipid barrier. SkinSpan™ also contains 200 mg of hyaluronic acid, which can bind large amounts of water and is also a component of the skin.
PhytoCellTec™ Md Nu, an innovative plant stem cell extract from Switzerland, is being researched in cosmetics. Complemented by DracoBelle™ Nu, a botanical extract from Moldavian dragonhead, SkinSpan™ brings modern longevity inspiration to your daily beauty routine.

SkinSpan™ provides important micronutrients for skin health and collagen formation: Vitamin C contributes to normal collagen formation for normal skin function. Copper contributes to the maintenance of normal connective tissue and protects cells from oxidative stress. Biotin, niacin, and riboflavin (vitamin B2) contribute to the maintenance of normal skin. Vitamin A (from beta-carotene) contributes to the maintenance of normal skin.
SkinSpan™ provides important micronutrients for skin health and collagen formation: Vitamin C contributes to normal collagen formation for normal skin function. Copper contributes to the maintenance of normal connective tissue and protects cells from oxidative stress. Biotin, niacin, and riboflavin (vitamin B2) contribute to the maintenance of normal skin. Vitamin A (from beta-carotene) contributes to the maintenance of normal skin.
With the antioxidant properties of vitamin C, copper, riboflavin, and beta-carotene, SkinSpan™ helps protect cells from oxidative stress - an important factor for an even, youthful-looking appearance.
SkinSpan™ provides Ceramosides™, a patented plant-based ceramide complex derived from wheat seeds. Ceramides are natural components of the skin's lipid barrier. SkinSpan™ also contains 200 mg of hyaluronic acid, which can bind large amounts of water and is also a component of the skin.
PhytoCellTec™ Md Nu, an innovative plant stem cell extract from Switzerland, is being researched in cosmetics. Complemented by DracoBelle™ Nu, a botanical extract from Moldavian dragonhead, SkinSpan™ brings modern longevity inspiration to your daily beauty routine.
SkinSpan™ provides important micronutrients for skin health and collagen formation: Vitamin C contributes to normal collagen formation for normal skin function. Copper contributes to the maintenance of normal connective tissue and protects cells from oxidative stress. Biotin, niacin, and riboflavin (vitamin B2) contribute to the maintenance of normal skin. Vitamin A (from beta-carotene) contributes to the maintenance of normal skin.
With the antioxidant properties of vitamin C, copper, riboflavin, and beta-carotene, SkinSpan™ helps protect cells from oxidative stress - an important factor for an even, youthful-looking appearance.
Understanding Skin Ageing Beyond Collagen: Why the Skin Barrier Is So Important for Appearance and Protection
Skin Health 101
When it comes to skin aging, almost everything revolves around collagen. But although collagen loss plays an important role, it is only part of the picture. The true foundation of healthy skin lies deeper: in the skin barrier.
This wafer-thin but highly complex layer of lipids, ceramides, and tightly connected skin cells is responsible for much more than just radiant skin. It regulates moisture balance, protects against irritants, and strengthens the skin's resilience at the cellular level. When it functions well, the skin barrier retains moisture, protects against environmental influences, and ensures an even complexion.
However, this barrier becomes more fragile with age. Biological changes affect the structure of the skin. Cell renewal slows down, the production of lipids, ceramides, and hyaluronic acid decreases, and collagen breakdown accelerates. The result: dryness, dull skin, fine lines, and increased sensitivity.
These processes often begin before visible collagen loss sets in and weaken the skin's ability to hydrate, renew, and protect itself from within.
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As we age, the skin barrier becomes increasingly fragile. The aging process triggers a series of biological changes that weaken the structural integrity of the skin - and this affects more than just the surface.
The skin gradually loses its ability to retain moisture, protect itself against irritants, and maintain its smooth, firm structure. The consequences include:- Reduced lipid and ceramide production – Ceramides and other skin lipids – often referred to as the “mortar” between skin cells – lock in moisture and strengthen the skin barrier. When their production decreases, the barrier becomes more permeable and prone to dryness.
- Decreasing hyaluronic acid content – The body's production of hyaluronic acid decreases with age. This leads to visible dryness, feelings of tightness, and loss of suppleness.
- Breakdown of collagen and elastin – Over time, these structural proteins break down faster than they are replaced. The skin becomes thinner, loses elasticity, and is more prone to fine lines.
- Slowed cell turnover – Skin renewal slows down, causing dead skin cells to accumulate on the surface and delaying deeper repair processes.
- Cumulative oxidative stress – Years of exposure to UV radiation and environmental pollution can further weaken the skin barrier.
With age, the skin barrier loses strength and needs targeted support to retain moisture, protect itself, and maintain its structure.
- Reduced lipid and ceramide production – Ceramides and other skin lipids – often referred to as the “mortar” between skin cells – lock in moisture and strengthen the skin barrier. When their production decreases, the barrier becomes more permeable and prone to dryness.

Feel the dıfference
A holistic skin formula. Clinical studies on the ingredients in SkinSpan show:
81%
noticed smoother skin (PhytoCellTec™ Md Nu)14 days
After just 14 days, the first visible differences in smoothness are apparentBaumann et al., 2024.
Skinspan™
30 capsules per bottleSkinspan™
30 capsules per bottleSkinSpan™ was developed in collaboration with longevity experts in Switzerland to support the skin's natural renewal process from within. The aim is to strengthen the skin structure and tackle the first signs of skin aging at an early stage.
The formula combines clinically tested ingredients:
- PhytoCellTec™ Md Nu – an innovative plant stem cell extract that is considered a modern ingredient in cosmetic research.
- Hyaluronic acid and Ceramosides™ – are naturally found in the skin structure and play a key role.
- Vitamin C and copper – contribute to normal collagen formation and the maintenance of normal connective tissue; they also help to protect cells from oxidative stress.
- DracoBelle™ Nu – is extracted from Moldavian dragonhead, a traditional plant that is receiving special attention in modern longevity research.
Through this multi-layered mode of action, SkinSpan™ helps to nourish the skin from within, support its natural structure, and make it more resistant to external influences. The result: skin that feels healthy, well-cared-for, and revitalized in the long term.
Take one capsule per day with food.
Active ingredients:
Hyaluronic acid (200 mg), Moldavian dragonhead extract – DracoBelle™ Nu (200 mg), vitamin C (80 mg), wheat seed extract – Ceramosides™ (30 mg), niacin / vitamin B3 (16 mg), PhytoCellTec™ Md Nu (10 mg, equivalent to 0.15 mg apple fruit cell culture biomass), beta-carotene (4.8 mg, equivalent to 800 µg vitamin A RE), riboflavin/vitamin B2 (1.4 mg), copper (1 mg), biotin (50 µg)
Other ingredients:
Microcrystalline cellulose as a filler to ensure that the capsule is completely filled (as the active ingredients alone may not take up enough volume); supports consistent manufacturing and dosing.
Magnesium salts of fatty acids as an anti-caking agent to keep the powder content free-flowing (important for processing) and ensure even distribution of the ingredients in the capsule (for correct dosing).
Hydroxypropyl methylcellulose (HPMC) as a coating agent in the form of a vegetable capsule shell.
Food Supplement with Hyaluronic Acid, Botanicals, Vitamins and Copper
Ingredients: Sodium Hyaluronate, Moldavian Dragonhead Extract (DracoBelle™ Nu), Glazing Agent (Hydroxypropyl Methyl Cellulose), L-Ascorbic Acid, Bulking Agent (Microcrystalline Cellulose), WHEAT Seed Extract (Ceramosides™), Beta Carotene, Nicotinamide, Apple Fruit Cell Culture Biomass (PhytoCellTec™ Md Nu), Anti-Caking Agent (Magnesium Salts of Fatty Acids), Cupric Gluconate, D-Biotin, Riboflavin.
Do not exceed recommended daily intake. Food supplements are not a substitute for a balanced and varied diet and a healthy lifestyle. Should only be consumed by persons over 18 years of age. If you are pregnant, nursing, have any medical condition, or taking any medication, please consult with a healthcare professional before use.
Store in a cool, dry place. Keep out of reach of young children.
Distributed in the EU by JDS Distribution BV, Priester Cuypersstraat 3, 1040 Etterbeek, Belgium. Distributed globally by Avea Life Inc. 3 Germay Dr, Wilmington, DE 19804 USA.
Quantity: 22.8 g (30 x 0.76 g)
At AVEA, we prioritise transparency and quality. We manufacture in Switzerland and source globally, focusing on ingredients with excellent bioavailability and high activity through standardised plant extracts. Every batch is rigorously double-tested for purity by an independent Swiss lab. We go beyond standard labelling to provide detailed information, and our customer service team is available for any questions or test result requests.
Active ingredients | Supplier | Production method |
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Sodium Hyaluronate (Hyaluronic Acid) | Productos Químicos Gonmisol S.A. | Fermentation |
Moldavian Dragonhead Extract (DracoBelle™ Nu) | Mibelle AG | Dracocephalum moldavica extraction |
L-Ascorbic Acid (Vitamin C) | Shanghai Freemen Chemicals Co., Ltd | Fermentation |
Wheat Seed Extract (Ceramosides™) | Seppic S.A | Triticum aestivum extraction and acetone purification |
Nicotinamide (Niacin, Vitamin B3) | dsm-firmenich AG | Chemical synthesis |
PhytoCellTec™ Md Nu (Apple Fruit Cell Culture Biomass) | Mibelle AG | Fruit cell culture extract |
Beta Carotene (Source of Vitamin A) | Lycored Corp | Fermentation |
Riboflavin (Vitamin B2) | Natural Alternatives International, Inc. (NAI) - Hubei Guangji Pharmaceutical Co., Ltd. | Fermentation |
Cupric Gluconate (Copper) | ECSA Chemicals AG | Chemical synthesis |
D-Biotin (Biotin) | dsm-firmenich AG | Chemical synthesis |
We ship worldwide, free delivery above 50£/€/CHF, 5-10 days from dispatch depending on your region.
Skinspan™
Pure, transparent ingredients – scientifically proven
Formulated with traceable, clinically tested ingredients. Developed and manufactured in Switzerland.

Ceramosides™
30 mgCeramosides™ are highly concentrated plant-based ceramides derived from wheat germ extract. Ceramides are components of the skin's natural lipid barrier.

PhytoCellTec™ Md Nu
10 mgThis patented stem cell extract is obtained from a rare Swiss apple variety. PhytoCellTec™ Md Nu is considered a pioneer among plant-based ingredients.

Hyaluronic Acid
200 mgHyaluronic acid is known for its exceptional water-binding capacity - it can store up to 1,000 times its own weight in moisture.

DracoBelle™ Nu
200 mgAlso known as Moldavian Dragonhead Extract, this clinically studied plant compound boosts cellular stress resistance and stimulates collagen production⁴. It also activates key cellular longevity pathways, which support skin firmness and elasticity.

Vitamin C
80 mgVitamin C is an essential nutrient for the skin, as it contributes to normal collagen formation for normal skin function. At the same time, it helps protect cells from oxidative stress - a factor that plays a role in premature skin aging.

Biotin
50 μgOften referred to as the “beauty vitamin,” biotin helps maintain normal skin, hair, and nails. It supports the skin's natural metabolism, ensuring a healthy, vibrant appearance.

Niacin (Vitamin B3)
16 mgNiacin contributes to maintaining normal skin and is known for harmonizing the complexion. It supports the skin barrier and contributes to an even, smooth complexion.

Copper
1 mgCopper plays a crucial role in skin structure as it contributes to the maintenance of normal connective tissue. It also protects skin cells from oxidative stress.

Beta Carotene
4.8 mgBeta-carotene is converted into vitamin A in the body, which helps maintain normal skin. It thus supports natural skin function and gives the complexion a healthy glow.

Riboflavin (Vitamin B2)
1.4 mgVitamin B2 not only contributes to maintaining normal skin, but also helps protect cells from oxidative stress. It thus supports the skin in defending itself against external influences day after day.
See full supplement facts

Third-party test results

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Serums and creams primarily act externally on the skin's surface. They can nourish and moisturize the skin, which is important for its health.
SkinSpan™, on the other hand, works from the inside: it directly supplies the skin cells with nutrients that have been proven to contribute to normal skin function:- Vitamin C contributes to normal collagen formation for normal skin function.
- Copper contributes to the maintenance of normal connective tissue and helps protect cells from oxidative stress.
- Vitamin A, biotin, niacin, and vitamin B2 contribute to the maintenance of normal skin.
In addition, SkinSpan™ combines these micronutrients with modern, plant-based ingredients such as Ceramosides™, PhytoCellTec™ Md Nu, and DracoBelle™ Nu, as well as hyaluronic acid, which have been carefully selected and studied.
The difference: While creams care for the skin externally, SkinSpan™ supports the skin from within - complementing your daily skincare routine on a deeper level.
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Take one capsule daily with a meal - ideally at the same time each day to promote regular intake.
Since the nutrients it contains are fat-soluble, we recommend taking it with a meal to optimize absorption. SkinSpan can be easily integrated into your morning or afternoon routine, helping you to keep track of your intake. -
Collagen supplements provide protein building blocks (amino acids) that the body can use to form collagen. This can support regeneration.
SkinSpan™ takes a different approach: the formula contains nutrients that have been proven to contribute to the maintenance of normal skin and support the body's own collagen structure:- Vitamin C contributes to normal collagen formation for normal skin function.
- Copper contributes to the maintenance of normal connective tissue and helps protect cells from oxidative stress.
- Vitamin A, biotin, niacin, and vitamin B2 contribute to the maintenance of normal skin.
While collagen supplements provide the body with raw materials for building, SkinSpan™ delivers the essential micronutrients that support the protection and functionality of the skin.
Both complement each other to form a more comprehensive strategy for beautiful skin.
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SkinSpan™ combines selected ingredients that have been scientifically tested and contribute to normal skin function.
- Vitamin C contributes to normal collagen formation for normal skin function.
- Vitamin A (from beta-carotene), biotin, riboflavin (vitamin B2), and niacin contribute to the maintenance of normal skin.
- Copper contributes to the maintenance of normal connective tissue and helps protect cells from oxidative stress.
- SkinSpan™ also contains other innovative ingredients such as Ceramosides™, hyaluronic acid, PhytoCellTec™ Md Nu, and DracoBelle™ Nu, which work synergistically to round out the formulation.
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Yes, SkinSpan™ is suitable for both vegans and vegetarians. All ingredients are 100% plant-based and free from animal components.
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Yes - the combination of SkinSpan and Collagen Activator makes sense, as both products complement each other perfectly.
Collagen Activator is based on Colgevity™ - a patented, vegan collagen precursor - and provides the three essential amino acids that are the building blocks of collagen, supplemented by scientifically proven co-factors such as vitamin C, AKG, and astaxanthin.
Together, they offer you holistic skin care from within - for visibly radiant, healthy skin with a scientific foundation. -
Yes, all ingredients in AVEA products are clinically tested and proven safe.
Each active compound – whether in our SkinSpan™ or other formulations – is backed by scientific studies that confirm both efficacy and safety. We carefully select the purest and most bioavailable plant extracts and compounds available. Our product descriptions clearly outline the production methods and origins of the ingredient.
AVEA manufactures in state-of-the-art, GMP-certified facilities that are regularly audited by Swiss authorities. Each product batch is sent to an independent Swiss laboratory for additional purity testing, ensuring the highest quality and safety.
Our SkinSpan™ is free from unnecessary additives – carefully developed to support your long-term health and skin from within.
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At AVEA, every formula begins with a deep understanding of the biological processes underlying aging - and how to positively influence them. Our work is based on the latest findings in cell health, metabolism, and longevity research.
Led by our co-founder and Chief Science Officer Sophie Chabloz, our in-house science team works closely with leading longevity researchers and biotech experts from renowned academic institutions. Together, we translate complex research into targeted, effective supplements.
Each supplement is based on clinically tested ingredients, is optimized for optimal bioavailability, and is thoroughly tested - so that what works in the lab can also be felt in everyday life. -
Your supplements will be shipped from our warehouse in the UK within 24 hours. We deliver worldwide and offer various shipping options: Standard shipping is free for orders over £50 and is carried out by the local postal service. For faster delivery, we also offer express shipping with commercial providers, depending on the destination.
All available shipping methods, estimated delivery times, and final shipping costs will be displayed at checkout.
If your country is not listed at checkout, please contact our customer service team at support@avea-life.com - we will find a solution for you. -
We recommend taking the food supplement regularly for at least three months to get the best possible experience of the ingredients.
If you are not satisfied after that, you can make use of our 90-day money-back guarantee.